Heroin Metabolism in the Body: How Heroin Affects the Brain INFOGRAPHIC
In particular, heroin and other MOP agonists are thought to increase dopamine concentrations in the terminal regions of the meso-striatal dopaminergic system by binding MOP located on inhibitory GABAergic neurons, hence disinhibiting dopamine neurons [143,144,145]. Yet, experimental evidence does not support https://ecosoberhouse.com/article/alternatives-to-alcohol/ the notion that the rewarding effects of heroin are mediated by dopaminergic transmission. […]
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